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General information. Pentasa is an aminosalicylate anti-inflammatory drug. It works by blocking the production of certain natural chemicals that may cause pain and swelling. Pentasa is used to treat ulcerative colitis, proctitis, and proctosigmoiditis. Mesalamine is also used to prevent the symptoms of ulcerative colitis from recurring. This drug may also be used to treat Crohn's disease.
Directions. Take Pentasa exactly as prescribed by your doctor. Take this medication by mouth with or without food, usually four times daily. Swallow the capsules whole. Do not chew or crush the capsules. Doing so can interfere with release of the drug into the colon. Dosage is based on your medical condition and response to therapy.
Precautions. Before taking Pentasa you should talk with your doctor if you have liver disease, liver failure, cirrhosis, kidney disease, kidney failure, congestive heart failure, pyloric stenosis, slow emptying of stomach, Crohn's disease, any allergies. Older adults may be more sensitive to the side effects of this drug. This medicine may cause stomach bleeding. Daily use of alcohol may increase your risk for stomach bleeding.
Overdose. If you think you have overdosed the medicine seek emergency medical help at once. The overdose symptoms are ringing in the ears, hearing loss, extreme tiredness, seizures, fast or difficult breathing, bloody vomit.
Contraindications. You should not take Pentasa if you are allergic to 5-aminosalicylic acid or to any of the ingredients of the medication, salicylates, or if you have gastric (stomach) or duodenal (intestinal) ulcer, urinary tract obstruction. It should not be used by a child younger than 2 years of age. Let your doctor know if you are pregnant or breastfeeding.
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